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・ Synaphe glaisalis
・ Synaphe infumatalis
・ Synaphe interjunctalis
・ Synaphe lorquinalis
・ Synaphe moldavica
・ Synaphe morbidalis
・ Synaphe oculatalis
・ Synaphe predotalis
・ Synaphe punctalis
・ Synaphe rungsi
・ Synaphe subolivalis
・ Synaphe testacealis
・ Synaphe unifascialis
・ Synaphea
・ Synaphea spinulosa
Synaphin protein domain
・ Synaphobranchus
・ Synaphobranchus calvus
・ Synaphobranchus dolichorhynchus
・ Synaphobranchus oregoni
・ Synaphridae
・ Synapomorphy
・ Synapscape
・ SyNAPSE
・ Synapse
・ Synapse (disambiguation)
・ Synapse (film)
・ Synapse (journal)
・ Synapse (magazine)
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Synaphin protein domain : ウィキペディア英語版
Synaphin protein domain

In molecular biology, Synaphin protein domain refers to a family of proteins consisting of several eukaryotic synaphin 1 and 2 proteins. Synaphin/complexin is a cytosolic protein that preferentially binds to syntaxin within the SNARE complex. Synaphin promotes SNAREs to form precomplexes that oligomerise into higher order structures. A peptide from the central, syntaxin binding domain of synaphin competitively inhibits these two proteins from interacting and prevents SNARE complexes from oligomerising. It is thought that oligomerisation of SNARE complexes into a higher order structure creates a SNARE scaffold for efficient, regulated fusion of synaptic vesicles. Synaphin promotes neuronal exocytosis by promoting interaction between the complementary syntaxin and synaptobrevin transmembrane regions that reside in opposing membranes prior to fusion.
==References==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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